Share Email Print
cover

Proceedings Paper

Micro patterning processes for thin film nitinol endografts and evaluation of endothelialization in swine model
Author(s): Youngjae Chun; Daniel S. Levi; K. P. Mohanchandra; Allan W. Tulloch; David A. Rigberg; Fernando Vinuela; Fernando Vinuela; Gregory P. Carman
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Micro features were created in thin film nitinol using a novel lift-off process to create an endovascular biomedical device. This manuscript describes fabrication problems with wet etching and introduces an effective way, named "Lift-off" process to solve undercut and non-uniform pattern issues. Two lift-off processes (i.e., lift-off I and II) are discussed. Lift-off I process has fracture issues and the film peels off the substrate due to high aspect ratio post structures. Lift-off II process use the film on the top of the Si substrate to fabricate various shape patterns (i.e., ellipse, diamond, circle, square, etc.) in the range of 5~60μm. The lift-off II process shows smooth and well aligned micro patterns in thin film nitinol. In-vivo tests in swine were performed to evaluate the endothelial tissue growth through fabricated micro patterns. Angiography and SEM images show patency of the artery and a uniform endothelial layer covering the device without thromobosis.

Paper Details

Date Published: 8 April 2010
PDF: 11 pages
Proc. SPIE 7650, Health Monitoring of Structural and Biological Systems 2010, 76502T (8 April 2010); doi: 10.1117/12.847588
Show Author Affiliations
Youngjae Chun, Univ. of California, Los Angeles (United States)
Daniel S. Levi, Univ. of California, Los Angeles (United States)
K. P. Mohanchandra, Univ. of California, Los Angeles (United States)
Allan W. Tulloch, Univ. of California, Los Angeles (United States)
David A. Rigberg, Univ. of California, Los Angeles (United States)
Fernando Vinuela, Univ. of California, Los Angeles (United States)
Fernando Vinuela, Univ. of California, Los Angeles (United States)
Gregory P. Carman, Univ. of California, Los Angeles (United States)


Published in SPIE Proceedings Vol. 7650:
Health Monitoring of Structural and Biological Systems 2010
Tribikram Kundu, Editor(s)

© SPIE. Terms of Use
Back to Top