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Proceedings Paper

Framework design and development of an informatics architecture for a systems biology approach to traumatic brain injury
Author(s): Adil Alaoui; Dongkyu Kim; Betty Levine; Kevin Cleary; Howard J. Federoff; Timothy Mhyre
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Paper Abstract

Traumatic Brain Injury (TBI) is a problem of major medical and socioeconomic significance, although the pathogenesis of its sequelae is not completely understood. As part of a large, multi-center project to study mild and moderate TBI, a database and informatics system to integrate a wide-range of clinical, biological, and imaging data is being developed. This database constitutes a systems-based approach to TBI with the goals of developing and validating biomarker panels that might be used to diagnose brain injury, predict clinical outcome, and eventually develop improved therapeutics. This paper presents the architecture for an informatics system that stores the disparate data types and permits easy access to the data for analysis.

Paper Details

Date Published: 12 March 2010
PDF: 8 pages
Proc. SPIE 7628, Medical Imaging 2010: Advanced PACS-based Imaging Informatics and Therapeutic Applications, 76280N (12 March 2010); doi: 10.1117/12.846090
Show Author Affiliations
Adil Alaoui, Georgetown Univ. Medical Ctr. (United States)
Dongkyu Kim, Georgetown Univ. Medical Ctr. (United States)
Betty Levine, Georgetown Univ. Medical Ctr. (United States)
Kevin Cleary, Georgetown Univ. Medical Ctr. (United States)
Howard J. Federoff, Georgetown Univ. Medical Ctr. (United States)
Timothy Mhyre, Georgetown Univ. Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 7628:
Medical Imaging 2010: Advanced PACS-based Imaging Informatics and Therapeutic Applications
Brent J. Liu; William W. Boonn, Editor(s)

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