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Proceedings Paper

Photoacoustic tomography of foreign bodies in soft biological tissue
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Paper Abstract

Ultrasound imaging suffers from poor sensitivity (~50%) and specificity in detecting small foreign bodies in tissue. Hence, alternative imaging methods are needed. Photoacoustic (PA) imaging takes advantage of strong optical absorption contrast and high ultrasonic resolution. This work employed a PA imaging system to detect foreign bodies in biological tissues. To achieve deep penetration, we used near-infrared light and a 5-MHz spherically focused ultrasonic transducer. PA images were obtained from objects (glass, wood, cloth, plastic, and metal) embedded in chicken tissue. The location and size of the targets from the PA images agreed well with those of the actual samples. Objects were imaged more than 1 cm deep. Spectroscopic PA imaging was also performed on the objects. These results suggest PA imaging can potentially be a useful intraoperative imaging tool to identify foreign bodies and discriminate viable tissues in wounded patients.

Paper Details

Date Published: 24 February 2010
PDF: 4 pages
Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75643H (24 February 2010); doi: 10.1117/12.845942
Show Author Affiliations
Xin Cai, Washington Univ. in St. Louis (United States)
Chulhong Kim, Washington Univ. in St. Louis (United States)
Manojit Pramanik, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 7564:
Photons Plus Ultrasound: Imaging and Sensing 2010
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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