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Proceedings Paper

Microfluidic cell separation: applications and challenges in tissue engineering
Author(s): Brian D. Plouffe; James V. Green; Shashi K. Murthy
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Paper Abstract

In tissue engineering, the enrichment of a particular cell type typically precedes in vitro culture on scaffolds. Another separation challenge that has emerged recently in tissue engineering is the need to isolate stem or progenitor cells that are naturally present in certain tissue types and have the ability to differentiate into functional cells. In both contexts, the ability of microfluidic systems to handle small sample volumes and achieve highly selective separation presents an attractive alternative to traditional techniques such as pre-plating, cell straining and sorting with fluorescent or magnetic tags.

Paper Details

Date Published: 18 February 2010
PDF: 10 pages
Proc. SPIE 7593, Microfluidics, BioMEMS, and Medical Microsystems VIII, 75930P (18 February 2010); doi: 10.1117/12.845774
Show Author Affiliations
Brian D. Plouffe, Northeastern Univ. (United States)
James V. Green, Northeastern Univ. (United States)
Shashi K. Murthy, Northeastern Univ. (United States)


Published in SPIE Proceedings Vol. 7593:
Microfluidics, BioMEMS, and Medical Microsystems VIII
Holger Becker; Wanjun Wang, Editor(s)

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