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Proceedings Paper

Detecting breast microcalcifications using super-resolution and wave-equation ultrasound imaging: a numerical phantom study
Author(s): Lianjie Huang; Francesco Simonetti; Peter Huthwaite; Robert Rosenberg; Michael Williamson
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Paper Abstract

Ultrasound image resolution and quality need to be significantly improved for breast microcalcification detection. Super-resolution imaging with the factorization method has recently been developed as a promising tool to break through the resolution limit of conventional imaging. In addition, wave-equation reflection imaging has become an effective method to reduce image speckles by properly handling ultrasound scattering/diffraction from breast heterogeneities during image reconstruction. We explore the capabilities of a novel super-resolution ultrasound imaging method and a wave-equation reflection imaging scheme for detecting breast microcalcifications. Super-resolution imaging uses the singular value decomposition and a factorization scheme to achieve an image resolution that is not possible for conventional ultrasound imaging. Wave-equation reflection imaging employs a solution to the acoustic-wave equation in heterogeneous media to backpropagate ultrasound scattering/diffraction waves to scatters and reconstruct images of heterogeneities. We construct numerical breast phantoms using in vivo breast images, and use a finite-difference wave-equation scheme to generate ultrasound data scattered from inclusions that mimic microcalcifications. We demonstrate that microcalcifications can be detected at full spatial resolution using the super-resolution ultrasound imaging and wave-equation reflection imaging methods.

Paper Details

Date Published: 12 March 2010
PDF: 10 pages
Proc. SPIE 7629, Medical Imaging 2010: Ultrasonic Imaging, Tomography, and Therapy, 762919 (12 March 2010); doi: 10.1117/12.844459
Show Author Affiliations
Lianjie Huang, Los Alamos National Lab. (United States)
Francesco Simonetti, Imperial College London (United Kingdom)
Peter Huthwaite, Imperial College London (United Kingdom)
Robert Rosenberg, Univ. of New Mexico (United States)
Michael Williamson, Univ. of New Mexico (United States)


Published in SPIE Proceedings Vol. 7629:
Medical Imaging 2010: Ultrasonic Imaging, Tomography, and Therapy
Jan D'hooge; Stephen A. McAleavey, Editor(s)

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