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Proceedings Paper

A groupwise mutual information metric for cost efficient selection of a suitable reference in cardiac computational atlas construction
Author(s): Corné Hoogendoorn; Tristan Whitmarsh; Nicolas Duchateau; Federico M. Sukno; Mathieu De Craene; Alejandro F. Frangi
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Paper Abstract

Computational atlases based on nonrigid registration have found much use in the medical imaging community. To avoid bias to any single element of the training set, there are two main approaches: using a (random) subject to serve as an initial reference and posteriorly removing bias, and a true groupwise registration with a constraint of zero average transformation for direct computation of the atlas. Major drawbacks are the possible selection of an outlier on one side, and an initialization with an invalid instance on the other. In both cases there is great potential for affecting registration performance, and producing a final average image in which the structure of interest deviates from the central anatomy of the population under study. We propose an inexpensive means of reference selection based on a groupwise correspondence measure, which avoids the selection of an outlier and is independent from the atlas construction approach that follows. Thus, it improves tractability of reference selection and robustness of automated atlas construction. We illustrate the method using a set of 20 cardiac multislice computed tomography volumes.

Paper Details

Date Published: 13 March 2010
PDF: 9 pages
Proc. SPIE 7623, Medical Imaging 2010: Image Processing, 76231R (13 March 2010); doi: 10.1117/12.844428
Show Author Affiliations
Corné Hoogendoorn, Univ. Pompeu Fabra (Spain)
Networking Biomedical Research Ctr. on Bioengineering (Spain)
Tristan Whitmarsh, Univ. Pompeu Fabra (Spain)
Networking Biomedical Research Ctr. on Bioengineering (Spain)
Nicolas Duchateau, Univ. Pompeu Fabra (Spain)
Networking Biomedical Research Ctr. on Bioengineering (Spain)
Federico M. Sukno, Networking Biomedical Research Ctr. on Bioengineering (Spain)
Univ. Pompeu Fabra (Spain)
Mathieu De Craene, Univ. Pompeu Fabra (Spain)
Networking Biomedical Research Ctr. on Bioengineering (Spain)
Alejandro F. Frangi, Univ. Pompeu Fabra (Spain)
Networking Biomedical Research Ctr. on Bioengineering (Spain)
Institucio Catalana de Recerca i Estudis Avancats (Spain)


Published in SPIE Proceedings Vol. 7623:
Medical Imaging 2010: Image Processing
Benoit M. Dawant; David R. Haynor, Editor(s)

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