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Proceedings Paper

Multi-beam x-ray source breast tomosynthesis reconstruction with different algorithms
Author(s): Weihua Zhou; Xin Qian; Jianping Lu; Otto Zhou; Ying Chen
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Paper Abstract

Digital breast tomosynthesis is a new technique to improve the early detection of breast cancer by providing threedimensional reconstruction volume of the object with limited-angle projection images. This paper investigated the image reconstruction with a standard biopsy training breast phantom using a novel multi-beam X-ray sources breast tomosynthesis system. Carbon nanotube technology based X-ray tubes were lined up along a parallel-imaging geometry to decrease the motion blur. Five representative reconstruction algorithms, including back projection (BP), filtered back projection (FBP), matrix inversion tomosynthesis (MITS), maximum likelihood expectation maximization (MLEM) and simultaneous algebraic reconstruction technique (SART), were investigated to evaluate the image reconstruction of the tomosynthesis system. Reconstructed images of the masses and micro-calcification clusters embedded in the phantom were studied. The evaluated multi-beam X-ray breast tomosynthesis system is able to generate three-dimensional information of the breast phantom with clearly-identified regions of the masses and calcifications. Future study will be done soon to further improve the imaging parameters' measurement and reconstruction.

Paper Details

Date Published: 19 March 2010
PDF: 8 pages
Proc. SPIE 7622, Medical Imaging 2010: Physics of Medical Imaging, 76220H (19 March 2010); doi: 10.1117/12.844295
Show Author Affiliations
Weihua Zhou, Southern Illinois Univ. (United States)
Xin Qian, The Univ. of North Carolina at Chapel Hill (United States)
Jianping Lu, The Univ. of North Carolina at Chapel Hill (United States)
Lineberger Comprehensive Cancer Ctr., The Univ. of North Carolina at Chapel Hill (United States)
Otto Zhou, The Univ. of North Carolina at Chapel Hill (United States)
Lineberger Comprehensive Cancer Ctr., The Univ. of North Carolina at Chapel Hill (United States)
Ying Chen, Southern Illinois Univ. (United States)


Published in SPIE Proceedings Vol. 7622:
Medical Imaging 2010: Physics of Medical Imaging
Ehsan Samei; Norbert J. Pelc, Editor(s)

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