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Proceedings Paper

Validation and detection of vessel landmarks by using anatomical knowledge
Author(s): Thomas Beck; Dominik Bernhardt; Christina Biermann; Rüdiger Dillmann
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Paper Abstract

The detection of anatomical landmarks is an important prerequisite to analyze medical images fully automatically. Several machine learning approaches have been proposed to parse 3D CT datasets and to determine the location of landmarks with associated uncertainty. However, it is a challenging task to incorporate high-level anatomical knowledge to improve these classification results. We propose a new approach to validate candidates for vessel bifurcation landmarks which is also applied to systematically search missed and to validate ambiguous landmarks. A knowledge base is trained providing human-readable geometric information of the vascular system, mainly vessel lengths, radii and curvature information, for validation of landmarks and to guide the search process. To analyze the bifurcation area surrounding a vessel landmark of interest, a new approach is proposed which is based on Fast Marching and incorporates anatomical information from the knowledge base. Using the proposed algorithms, an anatomical knowledge base has been generated based on 90 manually annotated CT images containing different parts of the body. To evaluate the landmark validation a set of 50 carotid datasets has been tested in combination with a state of the art landmark detector with excellent results. Beside the carotid bifurcation the algorithm is designed to handle a wide range of vascular landmarks, e.g. celiac, superior mesenteric, renal, aortic, iliac and femoral bifurcation.

Paper Details

Date Published: 13 March 2010
PDF: 8 pages
Proc. SPIE 7623, Medical Imaging 2010: Image Processing, 76234I (13 March 2010); doi: 10.1117/12.844266
Show Author Affiliations
Thomas Beck, Karlsruhe Institute of Technology (Germany)
Siemens Healthcare (Germany)
Dominik Bernhardt, Siemens Healthcare (Germany)
Christina Biermann, Siemens Healthcare (Germany)
Eberhard-Karls-Univ. of Tuebingen (Germany)
Rüdiger Dillmann, Karlsruhe Institute of Technology (Germany)


Published in SPIE Proceedings Vol. 7623:
Medical Imaging 2010: Image Processing
Benoit M. Dawant; David R. Haynor, Editor(s)

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