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Proceedings Paper

Improving visualization of intracranial arteries at the skull base for CT angiography with calcified plaques
Author(s): Adam Huang; Chung-Wei Lee; Chung-Yi Yang; Hon-Man Liu
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Paper Abstract

Bony structures at the skull base were the main obstacle to detection and estimation of arterial stenoses and aneurysms for CT angiography in the brain. Direct subtraction and the matched mask bone elimination (MMBE) have become two standard methods for removing bony structures. However, clinicians regularly find that calcified plaques at or near the carotid canal cannot be removed satisfactorily by existing methods. The blood-plaque boundary tends to be blurred by subtraction operation while plaque size is constantly overestimated by the bone mask dilation operation in the MMBE approach. In this study, we propose using the level of enhancement to adjust the MMBE bone mask more intelligently on the artery- and tissue-bone/plaque boundaries. The original MMBE method is only applied to the tissue-bone boundary voxels; while the artery-bone/blood-plaque boundary voxels, identified by a higher enhancement level, are processed by direct subtraction instead. A dataset of 6 patients (3 scanned with a regular dose and 3 scanned with a reduced dose) with calcified plaques at or near the skull base is used to examine our new method. Preliminary results indicate that the visualization of intracranial arteries with calcified plaques at the skull base can be improved effectively and efficiently.

Paper Details

Date Published: 9 March 2010
PDF: 8 pages
Proc. SPIE 7626, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, 76260E (9 March 2010); doi: 10.1117/12.844065
Show Author Affiliations
Adam Huang, National Central Univ. (Taiwan)
Chung-Wei Lee, National Taiwan Univ. Hospital (Taiwan)
Chung-Yi Yang, National Taiwan Univ. Hospital (Taiwan)
Hon-Man Liu, National Taiwan Univ. Hospital (Taiwan)
National Taiwan Univ. (Taiwan)

Published in SPIE Proceedings Vol. 7626:
Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging
Robert C. Molthen; John B. Weaver, Editor(s)

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