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Proceedings Paper

Rapid block matching based nonlinear registration on GPU for image guided radiation therapy
Author(s): An Wang; Brandon Disher; Greg Carnes; Terry M. Peters
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Paper Abstract

To compensate for non-uniform deformation due to patient motion within and between fractions in image guided radiation therapy, a block matching technique was adapted and implemented on a standard graphics processing unit (GPU) to determine the displacement vector field that maps the nonlinear transformation between successive CT images. Normalized cross correlation (NCC) was chosen as the similarity metric for the matching step, with regularization of the displacement vector field being performed by Gaussian smoothing. A multi-resolution framework was adopted to further improve the performance of the algorithm. The nonlinear registration algorithm was first applied to estimate the intrafractional motion from 4D lung CT images. It was also used to calculate the inter-fractional organ deformation between planning CT (PCT) and Daily Cone Beam CT (CBCT) images of thorax. For both experiments, manual landmark-based evaluation was performed to quantify the registration performance. In 4D CT registration, the mean TRE of 5 cases was 1.75 mm. In PCT-CBCT registration, the TRE of one case was 2.26mm. Compared to the CPU-based AtamaiWarp program, our GPU-based implementation achieves comparable registration accuracy and is ~25 times faster. The results highlight the potential utility of our algorithm for online adaptive radiation treatment.

Paper Details

Date Published: 27 February 2010
PDF: 10 pages
Proc. SPIE 7625, Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling, 762511 (27 February 2010); doi: 10.1117/12.843935
Show Author Affiliations
An Wang, Robarts Research Institute (Canada)
The Univ. of Western Ontario (Canada)
Brandon Disher, The Univ. of Western Ontario (Canada)
London Regional Cancer Program (Canada)
Greg Carnes, Robarts Research Institute (Canada)
The Univ. of Western Ontario (Canada)
Terry M. Peters, Robarts Research Institute (Canada)
The Univ. of Western Ontario (Canada)


Published in SPIE Proceedings Vol. 7625:
Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling
Kenneth H. Wong; Michael I. Miga, Editor(s)

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