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Proceedings Paper

Imaging properties of gold nanoparticles: CT number dependence study
Author(s): Shu-Ju Tu; Hui-Ling Hsieh; Tsi-Chian Chao
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Paper Abstract

In recent years, there has been a rapid research progress of molecular imaging technology. Many investigations in molecular imaging such as the nanoparticle applications in targeted drug delivery have been widely studied in several key small animal models. Various nanoparticles used as either the drug delivery carriers, imaging contrast mediums or target-specific therapeutic agents have established a novel research platform for biomedical related scientists and clinicians. Among these nanoparticles, gold nanoparticles have the unique non-toxic and stability properties. In this work, a commercially-available micro CT imaging system was used to specifically study the imaging properties for 15 nm spherical-shaped gold particles. Imaging properties were quantified by the CT numbers obtained from a series of photon energy levels in the micro CT scanner. We also compared the imaging results between gold nanoparticles and iodinated contrast medium to study the potential impact of gold nanoparticles served as the contrast agent.

Paper Details

Date Published: 22 March 2010
PDF: 8 pages
Proc. SPIE 7622, Medical Imaging 2010: Physics of Medical Imaging, 76222R (22 March 2010); doi: 10.1117/12.843887
Show Author Affiliations
Shu-Ju Tu, Chang Gung Univ. (Taiwan)
Hui-Ling Hsieh, Chang Gung Univ. (Taiwan)
Tsi-Chian Chao, Chang Gung Univ. (Taiwan)

Published in SPIE Proceedings Vol. 7622:
Medical Imaging 2010: Physics of Medical Imaging
Ehsan Samei; Norbert J. Pelc, Editor(s)

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