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Proceedings Paper

Tissue viability imaging for quantification of skin erythema and blanching
Author(s): Gert E. Nilsson; Martin J. Leahy
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Paper Abstract

Naked eye observation has up to recently been the main method of determining skin erythema (vasodilatation) and blanching (vasoconstriction) in skin testing. Since naked eye observation is a highly subjective and investigatordependent method, it is difficult to attain reproducibility and to compare results reported by different researchers performing their studies at different laboratories. Consequently there is a need for more objective, quantitative and versatile methods in the assessment of alterations in skin erythema and blanching caused by internal and external factors such as the intake of vasoactive drugs, application of agents on the skin surface and by constituents in the environment. Since skin microcirculation is sensitive to applied pressure and heat, such methods should preferably be noninvasive and designed for remote use without touching the skin. As skin microcirculation further possesses substantial spatial variability, imaging techniques are to be preferred before single point measurements. An emerging technology based on polarization digital camera spectroscopy - Tissue Viability Imaging (TiVi) - fulfills these requirements. The principles of TiVi (1) and some of its early applications (2-5) are addressed in this paper.

Paper Details

Date Published: 11 February 2010
PDF: 7 pages
Proc. SPIE 7563, Dynamics and Fluctuations in Biomedical Photonics VII, 756303 (11 February 2010); doi: 10.1117/12.843781
Show Author Affiliations
Gert E. Nilsson, Linköping Univ. (Sweden)
Martin J. Leahy, Univ. of Limerick and RSCI (Ireland)

Published in SPIE Proceedings Vol. 7563:
Dynamics and Fluctuations in Biomedical Photonics VII
Valery V. Tuchin; Donald D. Duncan; Kirill V. Larin, Editor(s)

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