Share Email Print

Proceedings Paper

Triple-energy contrast enhanced digital mammography
Author(s): Sylvie Puong; Pablo Milioni de Carvalho; Serge Muller
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

With the injection of iodine, Contrast Enhanced Digital Mammography (CEDM) provides functional information about breast tumour angiogenesis that can potentially help in cancer diagnosis. In order to generate iodine images in which the gray level is proportional to the iodine thickness, temporal and dual-energy approaches have already been considered. The dual-energy method offers the advantage of less patient motion artifacts and better comfort during the exam. However, this approach requires knowledge of the breast thickness at each pixel. Generally, as compression is applied, the breast thickness at each pixel is taken as the compression thickness. Nevertheless, in the breast border region, this assumption is not correct anymore and this causes inaccuracies in the iodine image. Triple-Energy CEDM could overcome these limitations by providing supplemental information in the form of a third image acquired with a different spectrum than the other two. This precludes the need of a priori knowledge of the breast thickness. Moreover, with Triple-Energy CEDM, breast thickness and glandularity maps could potentially be derived. In this study, we first focused on the method to recombine the three images in order to generate the iodine image, analyzing the performance of either quadratic, cubic or conic recombination functions. Then, we studied the optimal acquisition spectra in order to maximize the iodine SDNR in the recombined image for a given target total glandular dose. The concept of Triple-Energy CEDM was validated on simulated textured images and poly-energetic images acquired with a conventional X-ray mammography tube.

Paper Details

Date Published: 18 March 2010
PDF: 11 pages
Proc. SPIE 7622, Medical Imaging 2010: Physics of Medical Imaging, 762208 (18 March 2010); doi: 10.1117/12.843776
Show Author Affiliations
Sylvie Puong, GE Healthcare France (France)
Pablo Milioni de Carvalho, Telecom ParisTech (France)
Serge Muller, GE Healthcare France (France)

Published in SPIE Proceedings Vol. 7622:
Medical Imaging 2010: Physics of Medical Imaging
Ehsan Samei; Norbert J. Pelc, Editor(s)

© SPIE. Terms of Use
Back to Top