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Proceedings Paper

CMOS modulated light cameras for sensitive surface plasmon resonance imaging
Author(s): Nicholas S. Johnston; Roger A. Light; Ciaran E. Stewart; Mike G. Somekh; Mark C. Pitter
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Paper Abstract

Complementary metal oxide semiconductor (CMOS) cameras that can measure the phase and amplitude of periodically modulated optical signals have been developed. These allow parallel lock-in imaging at up to 256 x 256 pixels resolution without the need for slow and costly mechanical scanning. In conjunction with a differential surface plasmon resonance (dSPR) system, spatially resolved SPR imaging has been achieved with sensitivities of better than 10 microRIU per pixel per second. Results demonstrating the performance of modulated light cameras for dSPR imaging and high resolution SPR microscopy are presented and discussed.

Paper Details

Date Published: 17 February 2010
PDF: 11 pages
Proc. SPIE 7577, Plasmonics in Biology and Medicine VII, 75770H (17 February 2010); doi: 10.1117/12.843175
Show Author Affiliations
Nicholas S. Johnston, Institute of Biophysics, Imaging and Optical Science, Univ. of Nottingham (United Kingdom)
Roger A. Light, Institute of Biophysics, Imaging and Optical Science, Univ. of Nottingham (United Kingdom)
Ciaran E. Stewart, Electromagnetic Materials Group, Univ. of Exeter (United Kingdom)
Mike G. Somekh, Institute of Biophysics, Imaging and Optical Science, Univ. of Nottingham (United Kingdom)
Mark C. Pitter, Institute of Biophysics, Imaging and Optical Science, Univ. of Nottingham (United Kingdom)


Published in SPIE Proceedings Vol. 7577:
Plasmonics in Biology and Medicine VII
Tuan Vo-Dinh; Joseph R. Lakowicz, Editor(s)

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