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Proceedings Paper

Monitoring of tumor treatment using the combination of near-infrared laser light and carbon nanotubes
Author(s): Wei Chen; Feifan Zhou; Zhongmin Ou; Baoyan Wu; Sheng Song
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Paper Abstract

Single-walled carbon nanotubes (SWNTs) have a high optical absorbance in the near-infrared (NIR) region. In this special optical window, biological systems are known to be highly transparent. The optical properties of SWNTs provide an opportunity for selective photothermal therapy for cancer treatment. The application of single-walled carbon nanotubes (SWNTs) in the field of biomedicine is becoming an entirely new and exciting topic. Here, SWNTs are conjugated to integrin αvβ3 monoclonal antibody, which can bind specifically to the surface of the tumor markers. In vitro study revealed that SWNT-PEG-mAb presented a high targeting efficiency on integrin αvβ3-positive cells. Thus, SWNTs, combined with suitable tumor markers, can be used as novel nanomaterials for selective photothermal therapy for cancer treatment.

Paper Details

Date Published: 29 October 2009
PDF: 8 pages
Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 75190X (29 October 2009); doi: 10.1117/12.843072
Show Author Affiliations
Wei Chen, South China Normal Univ. (China)
Univ. of Central Oklahoma (United States)
Feifan Zhou, South China Normal Univ. (China)
Zhongmin Ou, South China Normal Univ. (China)
Baoyan Wu, South China Normal Univ. (China)
Sheng Song, South China Normal Univ. (China)


Published in SPIE Proceedings Vol. 7519:
Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009)
Qingming Luo; Lihong V. Wang; Valery V. Tuchin; Pengcheng Li; Ling Fu, Editor(s)

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