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Proceedings Paper

Clinical feasibility of rapid confocal melanoma feature detection
Author(s): Ricky Hennessy; Steve Jacques; Giovanni Pellacani; Daniel Gareau
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Paper Abstract

In vivo reflectance confocal microscopy shows promise for the early detection of malignant melanoma. One diagnostic trait of malignancy is the presence of pagetoid melanocytes in the epidermis. For automated detection of MM, this feature must be identified quantitatively through software. Beginning with in vivo, noninvasive confocal images from 10 unequivocal MMs and benign nevi, we developed a pattern recognition algorithm that automatically identified pagetoid melanocytes in all four MMs and identified none in five benign nevi. One data set was discarded due to artifacts caused by patient movement. With future work to bring the performance of this pattern recognition technique to the level of the clinicians on difficult lesions, melanoma diagnosis could be brought to primary care facilities and save many lives by improving early diagnosis.

Paper Details

Date Published: 2 March 2010
PDF: 7 pages
Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 75480Q (2 March 2010); doi: 10.1117/12.842824
Show Author Affiliations
Ricky Hennessy, Oregon Health & Science Univ. (United States)
Steve Jacques, Oregon Health & Science Univ. (United States)
Giovanni Pellacani, Univ. degli Studi di Modena e Reggio Emilia (Italy)
Daniel Gareau, Oregon Health & Science Univ. (United States)

Published in SPIE Proceedings Vol. 7548:
Photonic Therapeutics and Diagnostics VI
Anita Mahadevan-Jansen; Andreas Mandelis; Brian Jet-Fei Wong; Nikiforos Kollias; Henry Hirschberg; Kenton W. Gregory; Reza S. Malek; E. Duco Jansen; Guillermo J. Tearney; Steen J. Madsen; Bernard Choi; Justus F. R. Ilgner; Haishan Zeng; Laura Marcu, Editor(s)

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