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Proceedings Paper

Oblique-incidence spatially resolved diffuse reflectance spectroscopic diagnosis of skin cancer
Author(s): Alejandro Garcia-Uribe; Jun Zou; Tzu-Hsuan Chang; Madeleine Duvic; Victor Prieto; Lihong V. Wang
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Paper Abstract

This paper presents the use of spatially resolved oblique-incidence diffuse reflectance spectroscopy for skin cancer diagnosis. Spatio-spectral data from 166 pigmented skin lesions were collected for the wavelength range from 455 to 765 nm. A set of neural network based classifiers separates the pigmented malignant melanomas from the benign and dysplastic subgroups. A total of 110 lesions were used as the training set and 56 lesions were used as the testing set. This classifier performs with an overall 100% sensitivity and 92% specificity for the training set and 100% sensitivity and 88% specificity for the testing set. The second classifier was designed to separate the benign from the dysplastic subgroups. For the second classifier a total of 100 lesions were used as the training set and 51 lesions were used as the testing set. The overall classification rates were 94% and 88% for the training and testing sets respectively.

Paper Details

Date Published: 25 February 2010
PDF: 4 pages
Proc. SPIE 7572, Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics, 75720L (25 February 2010); doi: 10.1117/12.842781
Show Author Affiliations
Alejandro Garcia-Uribe, Washington Univ. in St. Louis (United States)
Texas A&M Univ. (United States)
Jun Zou, Texas A&M Univ. (United States)
Tzu-Hsuan Chang, Texas A&M Univ. (United States)
Madeleine Duvic, The Univ. of Texas M. D. Anderson Cancer Ctr. (United States)
Victor Prieto, The Univ. of Texas M. D. Anderson Cancer Ctr. (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 7572:
Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics
Gerard L. Coté, Editor(s)

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