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Proceedings Paper

Continuous acquisition scanner for whole-body multispectral optoacoustic tomography
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Paper Abstract

An essential problem dealing with three-dimensional optoacoustic imaging is the long data acquisition times associated with recording signals from multiple spatial projections, where signal averaging for each projection is applied to obtain satisfying signal-to-noise-ratio. This approach complicates acquisition and makes imaging challenging for most applications, especially for in vivo imaging and multispectral imaging. Instead we employ a herein introduced continuous data acquisition methodology that greatly shortens recording times over multiple projection angles and acquires high quality tomographic data without averaging. By this means a two dimensional image acquisition having 270 angular projections only takes about 9 seconds, while a full multispectral three dimensional image can normally take about 15 minutes to acquire with a single ultrasonic detector. The system performance is verified on tissue-mimicking phantoms containing known concentrations of fluorescent molecular agent as well as small animals.

Paper Details

Date Published: 23 February 2010
PDF: 6 pages
Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 756429 (23 February 2010); doi: 10.1117/12.842776
Show Author Affiliations
Rui Ma, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Vasilis Ntziachristos, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Daniel Razansky, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)

Published in SPIE Proceedings Vol. 7564:
Photons Plus Ultrasound: Imaging and Sensing 2010
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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