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Proceedings Paper

Fluorescent protein imaging with multispectral optoacoustic tomography
Author(s): Daniel Razansky; Martin Distel; Claudio Vinegoni; Rui Ma; Reinhard Köster; Vasilis Ntziachristos
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Paper Abstract

In this work, we have developed a selective-plane illumination multispectral optoacoustic tomography (MSOT) technique for high-resolution whole-body visualization of intact optically diffusive organisms whose sizes may vary from sub-millimeter up to a centimeter range and beyond. By combining multi-wavelength illumination, the method is shown capable of resolving tissue-specific expression of fluorescent proteins and other molecular biomarkers located deep in living optically diffuse tissues.

Paper Details

Date Published: 24 February 2010
PDF: 4 pages
Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75641R (24 February 2010); doi: 10.1117/12.842775
Show Author Affiliations
Daniel Razansky, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Martin Distel, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Claudio Vinegoni, Massachusetts General Hospital and Harvard Medical School (United States)
Rui Ma, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Reinhard Köster, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Vasilis Ntziachristos, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)


Published in SPIE Proceedings Vol. 7564:
Photons Plus Ultrasound: Imaging and Sensing 2010
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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