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Proceedings Paper

Measurement of the tear film and anterior chamber by confocal microscopy
Author(s): Kim K. Buttenschön; John M. Girkin; Clive G. Wilson; Daniel J. Daly
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Paper Abstract

We report on the development of a novel, low cost instrument that is capable of accurately measuring small, short and long term changes in the thickness of the cornea and tear film at high speed. The performance of the instrument was tested by measuring the influence of Allergan's OPTIVETM lubricating eye drops on the thickness of the cornea and tear film. Comparative measurements to quantify the performance were taken using Haag-Streit's LenStar. It was found that the newly developed instrument accurately measured a change in thickness of around 9 μm with an accuracy comparable to the LenStar, and with a standard deviation of less than 1 micrometer. Since the new instrument was not configured to resolve the tear film from the cornea, we are not yet able to distinguish the cause of the thickening.

Paper Details

Date Published: 2 March 2010
PDF: 6 pages
Proc. SPIE 7550, Ophthalmic Technologies XX, 755028 (2 March 2010); doi: 10.1117/12.842187
Show Author Affiliations
Kim K. Buttenschön, Durham Univ. (United Kingdom)
John M. Girkin, Durham Univ. (United Kingdom)
Clive G. Wilson, Univ. of Strathclyde (United Kingdom)
Daniel J. Daly, Lein Applied Diagnostics Ltd. (United Kingdom)

Published in SPIE Proceedings Vol. 7550:
Ophthalmic Technologies XX
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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