Share Email Print
cover

Proceedings Paper

Arrays of SOI photonic wire biosensors for label-free molecular detection
Author(s): Adam Densmore; Dan-Xia Xu; Martin Vachon; Siegfried Janz; Rubin Ma; Yunhui Li; Gregory Lopinski; Christian C. Luebbert; Qing Y. Liu; Jens H. Schmid; André Delâge; Pavel Cheben
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We present an SOI biosensor microarray chip that allows multiple molecular binding reactions to be simultaneously monitored. The individual biosensors are formed using 0.26 × 0.45 μm2 silicon photonic wire waveguides, which are arranged in compact Mach-Zehnder interferometer geometries with near temperature independent response. The sharp bend radius permitted by the photonic wires is exploited to form dense spiral waveguide structures that provide several millimeters of path length in a compact 130 μm diameter circular area. This design provides the high sensitivity of a long waveguide, while maintaining compatibility with commercial microarray spotting tools. For low volume analyte delivery the sensor array chip contains a monolithically integrated microfluidic channel formed in an SU-8 overlayer. Multiple antibody-antigen reactions are observed in real-time by using an infrared camera to monitor the optical powers emerging from the sensor array output waveguides.

Paper Details

Date Published: 16 February 2010
PDF: 8 pages
Proc. SPIE 7606, Silicon Photonics V, 76060C (16 February 2010); doi: 10.1117/12.842027
Show Author Affiliations
Adam Densmore, National Research Council Canada (Canada)
Dan-Xia Xu, National Research Council Canada (Canada)
Martin Vachon, National Research Council Canada (Canada)
Siegfried Janz, National Research Council Canada (Canada)
Rubin Ma, National Research Council Canada (Canada)
Yunhui Li, National Research Council Canada (Canada)
Gregory Lopinski, National Research Council Canada (Canada)
Christian C. Luebbert, National Research Council Canada (Canada)
Qing Y. Liu, National Research Council Canada (Canada)
Jens H. Schmid, National Research Council Canada (Canada)
André Delâge, National Research Council Canada (Canada)
Pavel Cheben, National Research Council Canada (Canada)


Published in SPIE Proceedings Vol. 7606:
Silicon Photonics V
Joel A. Kubby; Graham T. Reed, Editor(s)

© SPIE. Terms of Use
Back to Top