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Proceedings Paper

A meta-analysis of aneurysm formation in laser assisted vascular anastomosis (LAVA)
Author(s): Chen Chen; Fei Peng; Dahai Xu; Qinghua Cheng
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Paper Abstract

Laser assisted vascular anastomosis (LAVA) is looked as a particularly promising non-suture method in future. However, aneurysm formation is one of the main reasons delay the clinical application of LAVA. Some scientists investigated the incidence of aneurysms in animal model. To systematically analyze the literature on reported incidence of aneurysm formation in LAVA therapy, we performed a meta-analysis comparing LAVA with conventional suture anastomosis (CSA) in animal model. Data were systematically retrieved and selected from PUBMED. In total, 23 studies were retrieved. 18 studies were excluded, and 5 studies involving 647 animals were included. Analysis suggested no statistically significant difference between LAVA and CSA (OR 1.24, 95%CI 0.66-2.32, P=0.51). Result of meta analysis shows that the technology of LAVA is very close to clinical application.

Paper Details

Date Published: 29 October 2009
PDF: 6 pages
Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 751903 (29 October 2009); doi: 10.1117/12.841885
Show Author Affiliations
Chen Chen, Yangtze Univ. (China)
Fei Peng, Tongji Hospital, Huazhong Univ. of Science and Technology (China)
Dahai Xu, Yangtze Univ. (China)
Qinghua Cheng, Yangtze Univ. (China)


Published in SPIE Proceedings Vol. 7519:
Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009)

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