Share Email Print
cover

Proceedings Paper

Applications of fluorescence spectroscopy to problems of food safety: detection of fecal contamination and of the presence of central nervous system tissue and diagnosis of neurological disease
Author(s): Ramkrishna Adhikary; Sayantan Bose; Thomas A. Casey; Al Gapsch; Mark A. Rasmussen; Jacob W. Petrich
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Applications of fluorescence spectroscopy that enable the real-time or rapid detection of fecal contamination on beef carcasses and the presence of central nervous system tissue in meat products are discussed. The former is achieved by employing spectroscopic signatures of chlorophyll metabolites; the latter, by exploiting the characteristic structure and intensity of lipofuscin in central nervous system tissue. The success of these techniques has led us to investigate the possibility of diagnosing scrapie in sheep by obtaining fluorescence spectra of the retina. Crucial to this diagnosis is the ability to obtain baseline correlations of lipofuscin fluorescence with age. A murine model was employed as a proof of principle of this correlation.

Paper Details

Date Published: 17 February 2010
PDF: 15 pages
Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 757617 (17 February 2010); doi: 10.1117/12.841829
Show Author Affiliations
Ramkrishna Adhikary, Iowa State Univ. (United States)
Sayantan Bose, Iowa State Univ. (United States)
Thomas A. Casey, National Animal Disease Ctr., USDA (United States)
Al Gapsch, TECHnical SOLutions Group, Inc. (United States)
Mark A. Rasmussen, Ctr. for Veterinary Medicine, U.S. Food and Drug Administration (United States)
Jacob W. Petrich, Iowa State Univ. (United States)


Published in SPIE Proceedings Vol. 7576:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II
Samuel Achilefu; Ramesh Raghavachari, Editor(s)

© SPIE. Terms of Use
Back to Top