Share Email Print
cover

Proceedings Paper

Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia
Author(s): N. D. Gladkova; E. V. Zagaynova; O. S. Streltsova; E. B. Kiseleva; M. M. Karabut; L. B. Snopova; E. E. Yunusova; E. Tararova; V. M. Gelikonov
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

We consider the cross-polarization OCT (CP OCT) that is focused on comparison of images resulting from cross-polarization and co-polarization scattering simultaneously. This technique provides information about microstructural and biochemical alterations in depolarizing tissue components (collagen). We found that mature type I collagen gives a strong signal in orthogonal polarization. CP OCT images of benign inflammatory processes always feature signal in orthogonal polarization, with layers and borders persisting to be well defined. In the presence of precancerous alterations, signal in orthogonal polarization is available in the image but it is irregular, disappearing in some areas. A CP OCT image of bladder cancer in orthogonal polarization either shows no signal at all or a weak signal.

Paper Details

Date Published: 2 March 2010
PDF: 8 pages
Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 754813 (2 March 2010); doi: 10.1117/12.841810
Show Author Affiliations
N. D. Gladkova, Nizhny Novgorod State Medical Academy (Russian Federation)
E. V. Zagaynova, Nizhny Novgorod State Medical Academy (Russian Federation)
O. S. Streltsova, Nizhny Novgorod State Medical Academy (Russian Federation)
E. B. Kiseleva, Nizhny Novgorod State Medical Academy (Russian Federation)
M. M. Karabut, Nizhny Novgorod State Medical Academy (Russian Federation)
L. B. Snopova, Nizhny Novgorod State Medical Academy (Russian Federation)
E. E. Yunusova, Nizhny Novgorod State Medical Academy (Russian Federation)
E. Tararova, Nizhny Novgorod State Medical Academy (Russian Federation)
V. M. Gelikonov, Institute of Applied Physics (Russian Federation)


Published in SPIE Proceedings Vol. 7548:
Photonic Therapeutics and Diagnostics VI
Anita Mahadevan-Jansen; E. Duco Jansen; Andreas Mandelis; Brian Jet-Fei Wong; Justus F. R. Ilgner; Nikiforos Kollias; Bernard Choi; Haishan Zeng; Henry Hirschberg; Steen J. Madsen; Kenton W. Gregory; Guillermo J. Tearney; Laura Marcu; Reza S. Malek, Editor(s)

© SPIE. Terms of Use
Back to Top