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Proceedings Paper

Imaging of human skin lesions with the multispectral dermoscope
Author(s): Dimitrios Kapsokalyvas; Nicola Bruscino; Domenico Alfieri; Vincenzo de Giorgi; Giovanni Cannarozzo; Torello Lotti; Francesco S. Pavone
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Paper Abstract

The Dermoscope is a widespread and essential tool for dermatology. It reveals morphologic characteristics and aid the identification and diagnosis of a skin lesion. The diagnosis though is not always unambiguous and still the use of Dermoscopy doesn't obviate the need for histopathological verification. We report on the development of the Multispectral Dermoscope which employs high luminance LEDs with emission at three distinct spectral regions (470 nm, 530 nm, 625 nm). The illumination is polarized and an analyzer is used for the detection. Subsequent image analysis for enhancing the contrast for single scattered photons, hemoglobin absorption and melanin absorption is performed. Features like the surface texture of the skin, scattering structures in the epidermis, blood vessel morphology even in pigmented lesions and melanin localization have been observed in various skin pathologies. The device has been tested on volunteers and the features revealed have proven to be helpful in the diagnosis of skin lesions. Use of the Multispectral Dermoscope could improve the sensitivity and specificity of Dermoscopy.

Paper Details

Date Published: 2 March 2010
PDF: 8 pages
Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 754808 (2 March 2010); doi: 10.1117/12.841790
Show Author Affiliations
Dimitrios Kapsokalyvas, LENS - European Lab. for Non-Linear Spectroscopy, Univ. degli Studi di Firenze (Italy)
Nicola Bruscino, Univ. degli Studi di Firenze (Italy)
Domenico Alfieri, Light4Tech Firenze srl (Italy)
Vincenzo de Giorgi, Univ. degli Studi di Firenze (Italy)
Giovanni Cannarozzo, Univ. degli Studi di Firenze (Italy)
Torello Lotti, Univ. degli Studi di Firenze (Italy)
Francesco S. Pavone, LENS - European Lab. for Non-Linear Spectroscopy, Univ. degli Studi di Firenze (Italy)


Published in SPIE Proceedings Vol. 7548:
Photonic Therapeutics and Diagnostics VI
Anita Mahadevan-Jansen; E. Duco Jansen; Andreas Mandelis; Brian Jet-Fei Wong; Justus F. R. Ilgner; Nikiforos Kollias; Bernard Choi; Haishan Zeng; Henry Hirschberg; Steen J. Madsen; Kenton W. Gregory; Guillermo J. Tearney; Laura Marcu; Reza S. Malek, Editor(s)

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