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Proceedings Paper

Photon-cell interactive monte carlo (pciMC) model to describe both intracellular and extracellular optical pathways for biconcave red blood cells: phase function and albedo
Author(s): D. Sakota; S. Takatani
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Paper Abstract

A photon-cell interactive Monte Carlo ("pciMC") model was developed to quantify the intracellular optical propagation in a 3-dimensional biconcave red blood cell (RBC) model having a finite volume and intracellular hemoglobin. The orientation of RBCs with respect to the incident photons was randomized to allow either extra- or intra-cellular propagation depending on the incident point and angles where the photon propagation at the plasma-cell interface was determined by the Snell's law and Fresnell's law. In this study, the photon propagation through single RBC using the pciMC was compared against the Henyey-Greenstein phase function. The absorption dependent intracellular optical path length was evaluated in comparison to Mie theory. Both results showed good agreement. The pciMC can contribute to photo-spectroscopy of blood and tissues by quantifying both extra- and intra-cellular optical propagation.

Paper Details

Date Published: 26 February 2010
PDF: 10 pages
Proc. SPIE 7573, Biomedical Applications of Light Scattering IV, 757316 (26 February 2010); doi: 10.1117/12.841780
Show Author Affiliations
D. Sakota, Tokyo Medical and Dental Univ. (Japan)
S. Takatani, Tokyo Medical and Dental Univ. (Japan)

Published in SPIE Proceedings Vol. 7573:
Biomedical Applications of Light Scattering IV
Adam P. Wax; Vadim Backman, Editor(s)

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