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Proceedings Paper

Combined optical coherence tomography based on the extended Huygens-Fresnel principle and histology of mouse skin
Author(s): Shulian Wu; Zhifang Li; Hui Li; Xianghua Shi
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Paper Abstract

Noninvasive measurement technique to obtain tissue optical properties such as the scattering coefficient μs and the anisotropy factor g using optical coherence tomography (OCT) scattering model which based on the Extended Huygens-Fresnel principle is developed in our paper. Older and younger mouse-skin are as animal model to compare its scattering coefficient μs and the anisotropy factor g, the outcome shows that scattering coefficient μs is increased with the age of mouse-skin. Furthermore, we have made age's mouse-skin into H.E stain slices; the result of its morphology is consistent with the OCT imaging and OCT-EHF principle. All of that have provided the theoretical basis which to the research on photo-aging skin and photo-rejuvenation.

Paper Details

Date Published: 25 February 2010
PDF: 7 pages
Proc. SPIE 7568, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VIII, 756820 (25 February 2010); doi: 10.1117/12.841415
Show Author Affiliations
Shulian Wu, Fujian Normal Univ. (China)
Zhifang Li, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)
Xianghua Shi, Photop Technologies of Fuzhou (China)


Published in SPIE Proceedings Vol. 7568:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VIII
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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