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Proceedings Paper

Development of in vivo confocal microscope for reflection and fluorescence imaging simultaneously
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Paper Abstract

In-vivo confocal microscope technology can be applied to the medical imaging diagnosis and new drug development. We present an in-vivo confocal microscope that can acquire a reflection image and a fluorescence image simultaneously and independently. To obtain reflection confocal images, we used a linearly polarized diode laser with the wavelength of 830 nm. To acquire fluorescence confocal images, we used two diode lasers with the wavelength of 488 nm and 660 nm, respectively. Because of a broad wavelength bandwidth from visible (488 nm) to near-IR (830 nm), we designed and optimized the optical system to reduce various optical aberrations. With the developed in-vivo confocal microscope, we performed ex-vivo cell imaging and in-vivo imaging of the human skin.

Paper Details

Date Published: 25 February 2010
PDF: 8 pages
Proc. SPIE 7568, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VIII, 756821 (25 February 2010); doi: 10.1117/12.841223
Show Author Affiliations
MyoungKi Ahn, Korea Advanced Institute of Science and Technology (Korea, Republic of)
ByungSeon Chun, Korea Advanced Institute of Science and Technology (Korea, Republic of)
Cheol Song, Korea Advanced Institute of Science and Technology (Korea, Republic of)
DaeGab Gweon, Korea Advanced Institute of Science and Technology (Korea, Republic of)


Published in SPIE Proceedings Vol. 7568:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VIII
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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