Share Email Print
cover

Proceedings Paper

Synthesis, optical and microscopical characterization of albumin/porous silica/gold nanorods
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

We describe the synthesis of novel hybrid nanoparticles composed of a gold nanorods core and a bovine serum albuminconjugated porous silica shell. The pores of the porous silica shell are loaded with the cytotoxic surfactant cetrimonium bromide. Throughout the various steps of the synthesis, these nanoparticles exhibit excellent light extinction in a near infrared window around 700 - 900 nm, and good colloidal stability in aqueous environment. On replacement of the bovine serum albumin and cetrimonium bromide with functional macromolecules (e.g. antibodies) and appropriate drugs, this architecture may find application in a variety of biomedical applications including optical and photoacoustic diagnoses and imaging, photothermal and photoacoustic therapies and controlled drug release.

Paper Details

Date Published: 17 February 2010
PDF: 6 pages
Proc. SPIE 7577, Plasmonics in Biology and Medicine VII, 757715 (17 February 2010); doi: 10.1117/12.840963
Show Author Affiliations
Fulvio Ratto, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Sonia Centi, Univ. degli Studi di Firenze (Italy)
Paolo Matteini, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Francesca Rossi, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Roberto Pini, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)


Published in SPIE Proceedings Vol. 7577:
Plasmonics in Biology and Medicine VII
Tuan Vo-Dinh; Joseph R. Lakowicz, Editor(s)

© SPIE. Terms of Use
Back to Top