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Proceedings Paper

Smart pH cuvette for optical monitoring of pH of biological samples
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Paper Abstract

A Smart pH Cuvette is developed by coating the inner surface with pH sensitive thin film. The coating is a hydroscopic sol-gel material doped with colorimetric pH indicator dye sensitive to the pH of analyte solutions in biological range. Ocean optics miniaturized spectrometers are used for signal detection and analysis, along with multimode optical fibers. This new pH sensing arrangement yields an inexpensive solution for monitoring the pH of samples for biological applications. The Smart pH Cuvettes provide a resolution of 0.01 pH units, an accuracy of 1% of the reading, and 90% response in less than 10 seconds.

Paper Details

Date Published: 16 February 2010
PDF: 8 pages
Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 75761A (16 February 2010); doi: 10.1117/12.840670
Show Author Affiliations
Derek A. Guenther, Ocean Optics, Inc. (United States)
Mahmoud R. Shahriari, Ocean Optics, Inc. (United States)


Published in SPIE Proceedings Vol. 7576:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II
Samuel Achilefu; Ramesh Raghavachari, Editor(s)

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