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Proceedings Paper

In vivo XRF measurement of lead in bone: theory and important progress
Author(s): Weisong Yi; Xianqing Luo
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Paper Abstract

Lead is a leading environmental toxicant and Lead exposure has effects on many systems. Bone lead measured in vivo, has been shown to reflect cumulative lead exposure. Objective: To introduce and study in vivo XRF Measurements of Lead in Bone. Methods: Important progress and technology were summarized and introduced. Results: In vivo XRF is a safe and effective tool, which has enabled skeletal lead concentration measurement. X-ray spectrometry in vivo has contributed to the understanding of long-term human lead metabolism in ways that would not otherwise have happened. Conclusion: Efforts to introduce further improvements to the XRF technique are ongoing in order to lower its measurement uncertainty and enhance reproducibility. This may become especially important as the method becomes more widely used in the study of non-occupationally exposed populations, whose bone lead concentrations are generally quite low and thus comparable with the MDL of the standard XRF technique.

Paper Details

Date Published: 28 October 2009
PDF: 6 pages
Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 75190Q (28 October 2009); doi: 10.1117/12.839856
Show Author Affiliations
Weisong Yi, Huazhong Agricultural Univ. (China)
Xianqing Luo, Huazhong Agricultural Univ. (China)

Published in SPIE Proceedings Vol. 7519:
Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009)
Qingming Luo; Lihong V. Wang; Valery V. Tuchin; Pengcheng Li; Ling Fu, Editor(s)

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