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Proceedings Paper

Laser immunotherapy: initial results from a human breast cancer pilot trial
Author(s): Tomas Hode; Maria C. Guerra; Gabriela L. Ferrel; John A. Lunn; Orn Adelsteinsson; Robert E. Nordquist; Wei R. Chen
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Paper Abstract

Laser Immunotherapy is an experimental treatment modality for late-stage, metastatic tumors, which targets solid primary and/or secondary tumors and utilizes an autologous vaccine-like approach to stimulate immune responses. Specifically, laser immunotherapy combines laser-induced in situ tumor devitalization with an immunoadjuvant for local immunostimulation. Here we report the initial results from a human breast cancer pilot trial with laser immunotherapy. Six stage III and IV cancer patients were treated, all of which were considered to be out of all other options, and preliminary data at the three-month examination are presented. The immediate goal of the trial was to determine the patient tolerance and the toxicity of the therapy, the optimal dose for the alteration of the course of the disease, and the reduction of the tumor burden. Each patient was individually evaluated for toxicity tolerance through physical exams and by appropriate supplemental and routine laboratory tests. Observable tumors in patients were followed with physical examination and radiological evaluations. Treatment efficacy was judged by the size and number of local and distant metastases before and after treatment.

Paper Details

Date Published: 25 February 2010
PDF: 8 pages
Proc. SPIE 7565, Biophotonics and Immune Responses V, 756507 (25 February 2010); doi: 10.1117/12.839766
Show Author Affiliations
Tomas Hode, Immunophotonics Inc. (United States)
Maria C. Guerra, Immunophotonics Inc. (United States)
Gabriela L. Ferrel, Hospital Nacional Edgardo Rebagliati Martins (Peru)
John A. Lunn, Consultant (Bahamas)
Orn Adelsteinsson, International Strategic Cancer Alliance (United States)
Robert E. Nordquist, Immunophotonics Inc. (United States)
Wei R. Chen, Univ. of Central Oklahoma (United States)

Published in SPIE Proceedings Vol. 7565:
Biophotonics and Immune Responses V
Wei R. Chen, Editor(s)

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