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Proceedings Paper

Spectroscopy of several drugs in the terahertz region
Author(s): Guifeng Liu; Shihua Ma; Xiyu Song; Peng Zhang; Haixia Li; Wenfeng Wang
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Paper Abstract

We use terahertz time-domain spectroscopy (THz-TDS) to measure the absorption spectra of six drugs, atenolol, furosemide, tropicamide, lobeline hydrochloride, propranolol hydrochloride, and promethazine hydrochloride, in the frequency range of 0.3 THz to 2.0 THz. Furosemide, tropicamide, and promethazine hydrochloride show distinct absorption features, whereas atenolol, lobeline hydrochloride, and propranolol hydrochloride exhibit no obvious absorption peaks. The use of THz-TDS makes it possible to rapidly distinguish the drugs with characteristic absorption peaks. Our results demonstrate that THz-TDS is highly sensitive to the structure and spatial arrangement of molecules. As a result, THz-TDS will have potential exploitation in pharmaceutical fields.

Paper Details

Date Published: 5 August 2009
PDF: 6 pages
Proc. SPIE 7385, International Symposium on Photoelectronic Detection and Imaging 2009: Terahertz and High Energy Radiation Detection Technologies and Applications, 738527 (5 August 2009); doi: 10.1117/12.834452
Show Author Affiliations
Guifeng Liu, Shanghai Institute of Applied Physics (China)
Graduate Univ. of CAS (China)
Shihua Ma, Shanghai Institute of Applied Physiys (China)
Xiyu Song, Shanghai Institute of Applied Physics (China)
Graduate Univ. of CAS (China)
Peng Zhang, Shanghai Institute of Applied Physics (China)
Graduate Univ. of CAS (China)
Haixia Li, Shanghai Institute of Applied Physics (China)
Graduate Univ. of CAS (China)
Wenfeng Wang, Shanghai Institute of Applied Physics (China)


Published in SPIE Proceedings Vol. 7385:
International Symposium on Photoelectronic Detection and Imaging 2009: Terahertz and High Energy Radiation Detection Technologies and Applications
X.-C. Zhang; James M. Ryan; Cun-lin Zhang; Chuan-xiang Tang, Editor(s)

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