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Proceedings Paper

Blood flow measurement in the in vivo mouse model by the combination of Doppler OCT and the signal power decrease in spectral domain OCT
Author(s): Julia Walther; Gregor Mueller; Henning Morawietz; Edmund Koch
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Paper Abstract

Blood flow measurement with spectrometer-based Fourier domain optical coherence tomography (FD OCT) is limited by the motion-induced signal fading and the resulting reduction of flow sensitivity. In this study, a combination of the established Doppler OCT and the numerically simulated signal damping due to obliquely moved scatterers is used to estimate the systolic blood flow velocities in the in vivo mouse model at which the standard Doppler OCT does not work any longer.

Paper Details

Date Published: 14 July 2009
PDF: 7 pages
Proc. SPIE 7372, Optical Coherence Tomography and Coherence Techniques IV, 73721Y (14 July 2009); doi: 10.1117/12.831836
Show Author Affiliations
Julia Walther, Clinic of Anaesthesiology and Intensive Care Medicine (Germany)
Gregor Mueller, Medical Faculty Carl Gustav Carus, Dresden Univ. of Technology (Germany)
Henning Morawietz, Medical Faculty Carl Gustav Carus, Dresden Univ. of Technology (Germany)
Edmund Koch, Clinic of Anaesthesiology and Intensive Care Medicine (Germany)


Published in SPIE Proceedings Vol. 7372:
Optical Coherence Tomography and Coherence Techniques IV
Peter E. Andersen; Brett E. Bouma, Editor(s)

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