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Proceedings Paper

Three-dimensional bone imaging: optical coherence tomography versus micro computer tomography
Author(s): Christoph Kasseck; Marita Kratz; Antonia Torcasio; Nils C. Gerhardt; G. Harry van Lenthe; Thilo Gambichler; Klaus Hoffmann; David B. Jones; Martin R. Hofmann
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Paper Abstract

Optical coherence tomography (OCT) and micro-computed tomography (μCT) were applied to a bone sample, a 3x4x4mm cube of fixed substantia spongiosa from an arthritic human hip. Three-dimensional image sets (1.0mm x 0.9mm x 1.6mm) were acquired with both imaging systems for the same volume of interest. For better navigation, the sample surface was additionally imaged with microscopy. The resulting OCT images were compared stepwise to the according μCT images, showing a high correlation regarding the visualization of individual trabeculae. System based imaging differences were also found: due to scattering, OCT is limited to an imaging depth of about 1mm, while μCT is capable of imaging the complete trabecular bone architecture. However, OCT images cells and the inner bone structures in contrast to μCT at similar nominal resolutions (5μm respectively 6.5μm).

Paper Details

Date Published: 13 July 2009
PDF: 7 pages
Proc. SPIE 7372, Optical Coherence Tomography and Coherence Techniques IV, 73721B (13 July 2009); doi: 10.1117/12.831814
Show Author Affiliations
Christoph Kasseck, Ruhr-Univ. Bochum (Germany)
Marita Kratz, Philipps Univ. Marburg (Germany)
Antonia Torcasio, Katholieke Univ. Leuven (Belgium)
Nils C. Gerhardt, Ruhr-Univ. Bochum (Germany)
G. Harry van Lenthe, Katholieke Univ. Leuven (Belgium)
Thilo Gambichler, St. Josef Hospital (Germany)
Klaus Hoffmann, St. Josef Hospital (Germany)
David B. Jones, Philipps Univ. Marburg (Germany)
Martin R. Hofmann, Ruhr-Univ. Bochum (Germany)

Published in SPIE Proceedings Vol. 7372:
Optical Coherence Tomography and Coherence Techniques IV
Peter E. Andersen; Brett E. Bouma, Editor(s)

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