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Proceedings Paper

Photoacoustic NO detection for asthma diagnostics
Author(s): Markus Germer; Marcus Wolff; Hermann Harde
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Paper Abstract

Exhaled nitric oxide was of high interest in breath analyses in the past few years. After its first detection in human breath in 1991, numerous publications uncovered the role of NO and its relation to different diseases. A strong relationship between an asthmatic eosinophilic airway inflammation and an increased NO level is medically confirmed. In this study a new photoacoustic detection system for nitric oxide based on a pulsed quantum cascade laser is introduced. The laser's single mode emission provides adequate selectivity to differentiate NO from other molecules in the sample. The demonstrated detection sensitivity allows in principle an application of the new system as diagnostic tool for asthma.

Paper Details

Date Published: 9 July 2009
PDF: 6 pages
Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 73710Q (9 July 2009); doi: 10.1117/12.831774
Show Author Affiliations
Markus Germer, Hamburg Univ. of Applied Sciences (Germany)
Marcus Wolff, Hamburg Univ. of Applied Sciences (Germany)
Hermann Harde, Helmut-Schmidt-Univ. (Germany)


Published in SPIE Proceedings Vol. 7371:
Novel Optical Instrumentation for Biomedical Applications IV
Christian D. Depeursinge; I. Alex Vitkin, Editor(s)

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