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Proceedings Paper

Fiber bundle based fluorescence tomography system for human breast imaging
Author(s): Yuting Lin; Orhan Nalcioglu; Gultekin Gulsen
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Paper Abstract

Fluorescence diffuse optical tomography (FT) is a promising molecular imaging technique that can spatially resolve both fluorophore concentration and lifetime parameters. In this phantom study, we built a photo-multiplier tube (PMT) based single detection system that uses fiber bundles to collect light. Measurements were acquired both with a 1 mm diameter single fiber and a 6 mm diameter fiber bundle using the very same detection unit for comparison purposes. We demonstratethat the fluorescence concentration and lifetime can be well recovered for 6 mm diameter objects deeply embedded in an 80 mm diameter breast-sized phantom when the fiber bundle is utilized.

Paper Details

Date Published: 9 July 2009
PDF: 8 pages
Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 737108 (9 July 2009); doi: 10.1117/12.831770
Show Author Affiliations
Yuting Lin, Ctr. for Functional Onco-Imaging, Univ. of California, Irvine (United States)
Orhan Nalcioglu, Ctr. for Functional Onco-Imaging, Univ. of California, Irvine (United States)
Gultekin Gulsen, Ctr. for Functional Onco-Imaging, Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 7371:
Novel Optical Instrumentation for Biomedical Applications IV
Christian D. Depeursinge; I. Alex Vitkin, Editor(s)

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