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Proceedings Paper

Ultrasound-transmission parameter imaging in a photoacoustic imager
Author(s): J. Jose; R. Willemink; S. Resink; T. Maalderink; J. C. G. van Hespen; T. G. van Leeuwen; S. Manohar
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Paper Abstract

We present a 'hybrid' imaging system, which can image both optical absorption properties and acoustic transmission properties of an object in a two-dimensional slice using a computed tomography photoacoustic imager. The ultrasound transmission measurement method uses a strong absorber of light which is placed in the path of the light illuminating the sample. This acts as a source of ultrasound, whose interaction with the sample can be measured at the far-end of the sample using the same ultrasound detector used for photoacoustics. Such measurements are made at various angles around the sample in a computerized tomography approach. The ultrasound transients at the multi-element detector at all projections are analyzed for both times-of-arrival and amplitude. Using a fan-beam projection reconstruction algorithm we obtain hybrid images of optical absorption, speed-of-sound and acoustic attenuation. We validate the method on an appropriate phantom.

Paper Details

Date Published: 9 July 2009
PDF: 8 pages
Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 73710S (9 July 2009); doi: 10.1117/12.831732
Show Author Affiliations
J. Jose, MIRA Institute for Biomedical Technology and Technical Medicine, Univ. of Twente (Netherlands)
R. Willemink, Univ. of Twente (Netherlands)
S. Resink, MIRA Institute for Biomedical Technology and Technical Medicine, Univ. of Twente (Netherlands)
T. Maalderink, MIRA Institute for Biomedical Technology and Technical Medicine, Univ. of Twente (Netherlands)
J. C. G. van Hespen, MIRA Institute for Biomedical Technology and Technical Medicine, Univ. of Twente (Netherlands)
T. G. van Leeuwen, MIRA Institute for Biomedical Technology and Technical Medicine, Univ. of Twente (Netherlands)
Biomedical Photonics, Academic Medical Ctr., Univ. van Amsterdam (Netherlands)
S. Manohar, MIRA Institute for Biomedical Technology and Technical Medicine, Univ. of Twente (Netherlands)


Published in SPIE Proceedings Vol. 7371:
Novel Optical Instrumentation for Biomedical Applications IV
Christian D. Depeursinge; I. Alex Vitkin, Editor(s)

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