Share Email Print
cover

Proceedings Paper

A safe, low-cost, and portable instrumentation for bedside time-resolved picosecond near infrared spectroscopy
Author(s): Marine Amouroux; Wilfried Uhring; Thierry Pebayle; Patrick Poulet; Luc Marlier
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Continuous wave Near InfraRed Spectroscopy (NIRS) has been used successfully in clinical environments for several years to detect cerebral activation thanks to oxymetry (i.e. absorption of photons by oxy- and deoxy- hemoglobin) measurement. The goal of our group is to build a clinically-adapted time-resolved NIRS setup i.e. a setup that is compact and robust enough to allow bedside measurements and that matches safety requirements with human patients applications. Indeed our group has already shown that time resolution allows spatial resolution and improves sensitivity of cerebral activation detection. The setup is built with four laser diodes (excitation wavelengths: 685, 780, 830 and 870 nm) whose emitted light is injected into four optical fibers; detection of reflected photons is made through an avalanche photodiode and a high resolution timing module used to record Temporal Point Spread Functions (TPSF). Validation of the device was made using cylindrically-chaped phantoms with absorbing and/or scattering inclusions. Results show that recorded TPSF are typical both of scattering and absorbing materials thus demonstrating that our apparatus would detect variation of optical properties (absorption and scattering) deep within a diffusive media just like a cerebral activation represents a rise of absorption in the cortex underneath head surface.

Paper Details

Date Published: 9 July 2009
PDF: 5 pages
Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 73710C (9 July 2009); doi: 10.1117/12.831729
Show Author Affiliations
Marine Amouroux, Lab. d'Imagerie et de Neurosciences Cognitives, CNRS, Univ. de Strasbourg (France)
Wilfried Uhring, Institut d'Electronique du Solide et des Systèmes, CNRS, Univ. de Strasbourg (France)
Thierry Pebayle, Lab. d'Imagerie et de Neurosciences Cognitives, CNRS, Univ. de Strasbourg (France)
Patrick Poulet, Lab. d'Imagerie et de Neurosciences Cognitives, CNRS, Univ. de Strasbourg (France)
Luc Marlier, Lab. d'Imagerie et de Neurosciences Cognitives, CNRS, Univ. de Strasbourg (France)


Published in SPIE Proceedings Vol. 7371:
Novel Optical Instrumentation for Biomedical Applications IV
Christian D. Depeursinge; I. Alex Vitkin, Editor(s)

© SPIE. Terms of Use
Back to Top