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Proceedings Paper

Monitoring of epithelium capillary density
Author(s): Rajesh Kanawade; Gennadiy Saiko; Alexandre Douplik
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Paper Abstract

Monitoring the epithelium vessel capillary density pattern is critically important for preventing rapidly developing life threatening syndromes such as shock or systemic organ failures. The objective of this study is real time monitoring of epithelium vessel density pattern. The fiber sensor will be based on spatially resolved diffuse reflectance spectra. The parameters comprising period and depth of capillary spatial modulation are exploited for shock detection. The preliminary investigations with simulated spectra have shown that the new method can reasonably extracts minor deviations of oxygenation and local volume blood fraction - parameters, directly related to the local vessel density. The original method developed to use these parameters is much less dependent on light scattering in visible range as opposed to the most of the currently used methods.

Paper Details

Date Published: 9 July 2009
PDF: 5 pages
Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 73711L (9 July 2009); doi: 10.1117/12.831725
Show Author Affiliations
Rajesh Kanawade, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)
Gennadiy Saiko, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)
Alexandre Douplik, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)


Published in SPIE Proceedings Vol. 7371:
Novel Optical Instrumentation for Biomedical Applications IV
Christian D. Depeursinge; I. Alex Vitkin, Editor(s)

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