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Proceedings Paper

Biomaterials based on DNA embedded in silica matrix
Author(s): Maria Mihaly; Alina Comanescu; Adina Rogozea; Cristian Pirvu; Ileana Rau
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Paper Abstract

Ordered DNA - silica materials have been efficiently synthesized by using the microemulsion sol - gel procedure. Dynamic Light Scattering (DLS) spectra showed that the microemulsion systems applied for DNA - silica materials synthesis contain structural units similar in size and shape. The atomic force microscopy (AFM) analysis revealed that the obtained DNA - silica thin films exhibit an ordered units array pattern structure in micron scale and the structural units channels run parallel with each. The UV - VIS reflectance spectra performed for DNA/Rhodamine - silica materials proved that the structure and properties of native DNA are protected by incorporation. The obtained results assumed a globular shape of the DNA imposed by microemulsion template and the chromophore location into its double helix structure. An improvement of the thermal properties of DNA, incorporated into the DNA - silica material, was observed by the thermogravimetric-differential thermal analysis (TGA-DTA).

Paper Details

Date Published: 20 August 2009
PDF: 9 pages
Proc. SPIE 7403, Nanobiosystems: Processing, Characterization, and Applications II, 740308 (20 August 2009); doi: 10.1117/12.828853
Show Author Affiliations
Maria Mihaly, Univ. Politehnica Bucharest (Romania)
Alina Comanescu, Univ. Politehnica Bucharest (Romania)
Adina Rogozea, Ilie Murgulescu Institute of Physical Chemistry (Romania)
Cristian Pirvu, Univ. Politehnica Bucharest (Romania)
Ileana Rau, Univ. Politehnica Bucharest (Romania)

Published in SPIE Proceedings Vol. 7403:
Nanobiosystems: Processing, Characterization, and Applications II
Norihisa Kobayashi; Fahima Ouchen; Ileana Rau, Editor(s)

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