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Proceedings Paper

Strategies for targeted antimicrobial photodynamic therapy
Author(s): Sarika Verma; Ulysses Sallum; Xiang Zheng; Tayyaba Hasan
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Paper Abstract

The photophysics and mechanisms of cell killing by photodynamic therapy (PDT) have been extensively studied in recent years, and PDT has received regulatory approval for the treatment of a number of diseases worldwide. As the application of this treatment modality expands with regard to both anatomical sites and diseases, it is important to develop strategies for enhancing PDT outcomes. Our group has focused on developing targeting strategies to enhance PDT for both cancerous as well as anti-microbial applications. In this article, we will discuss photosensitizer modification and conjugation strategies for targeted antimicrobial photodynamic therapy.

Paper Details

Date Published: 13 July 2009
PDF: 7 pages
Proc. SPIE 7380, Photodynamic Therapy: Back to the Future, 73803J (13 July 2009); doi: 10.1117/12.828203
Show Author Affiliations
Sarika Verma, Wellman Ctr. for Photomedicine, MGH (United States)
Harvard Medical School (United States)
Ulysses Sallum, Wellman Ctr. for Photomedicine, MGH (United States)
Harvard Medical School (United States)
Xiang Zheng, Wellman Ctr. for Photomedicine, MGH (United States)
Harvard Medical School (United States)
Tayyaba Hasan, Wellman Ctr. for Photomedicine, MGH (United States)
Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 7380:
Photodynamic Therapy: Back to the Future

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