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Proceedings Paper

Theoretical prediction for cell deformation in the optical traps
Author(s): Paul B. Bareil; Yunlong Sheng; Arthur E. Chiou
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Paper Abstract

We present optical and mechanical models for cell's deformation in the optical traps. The morphological deformation of the cell is calculated from the local stress distribution on the cell using the linear theory of thin elastic membrane, which is valid for the cells without internal cytoskeletal structure, such as the red blood cells. This generic approach allows computing for a variety of experimental configurations and predicting cell's deformation. Comparison of the results with numerical calculation tool such as Mie scattering and T-Matrix is made. The coupling coefficient from one fiber to another through the deformed trapped cell in the fiber-optical dual-beam stretcher was calculated for fast monitoring of the cell deformation.

Paper Details

Date Published: 20 August 2009
PDF: 7 pages
Proc. SPIE 7400, Optical Trapping and Optical Micromanipulation VI, 74000D (20 August 2009); doi: 10.1117/12.826638
Show Author Affiliations
Paul B. Bareil, Univ. Laval (Canada)
Yunlong Sheng, Univ. Laval (Canada)
Arthur E. Chiou, National Yang-Ming Univ. (Taiwan)

Published in SPIE Proceedings Vol. 7400:
Optical Trapping and Optical Micromanipulation VI
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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