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Proceedings Paper

Photodynamic therapy of cervical intraepithelial neoplasia using hexaminolevulinate and methylaminolevulinate
Author(s): Philipp Soergel; Ismini Staboulidou; Herrmann Hertel; Cordula Schippert; Peter Hillemanns
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Paper Abstract

Cervical intraepithelial neoplasia (CIN) is the precursor of invasive cervical cancer. Previous studies indicated that photodynamic therapy (PDT) represents an effective treatment modality in CIN. In 28 patients with CIN 1 - 3, 1 - 2 cycles of PDT were conducted using hexaminolevulinate (HAL) or methylaminolevulinate (MAL) and a special light delivery system. After 6 months, biopsies were obtained to assess response. The overall response rate for complete or partial response was 65%. Photodynamic therapy using new ALA esters is effective and may offer unique advantages in the therapy of CIN.

Paper Details

Date Published: 13 July 2009
PDF: 4 pages
Proc. SPIE 7380, Photodynamic Therapy: Back to the Future, 738031 (13 July 2009); doi: 10.1117/12.824462
Show Author Affiliations
Philipp Soergel, Hannover Medical School (Germany)
Ismini Staboulidou, Hannover Medical School (Germany)
Herrmann Hertel, Hannover Medical School (Germany)
Cordula Schippert, Hannover Medical School (Germany)
Peter Hillemanns, Hannover Medical School (Germany)


Published in SPIE Proceedings Vol. 7380:
Photodynamic Therapy: Back to the Future
David H. Kessel, Editor(s)

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