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Proceedings Paper

In vivo office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography
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Paper Abstract

Optical coherence tomography (OCT) is an evolving noninvasive imaging modality and has been used to image the human larynx during surgical endoscopy. The design of a long GRIN lens based probe capable of capturing images of the human larynx by use of swept-source OCT during a typical office-based laryngoscopy examination is presented. In vivo OCT imaging of the human larynx is demonstrated with 40 fame/second. Dynamic vibration of the vocal folds is recorded to provide not only high-resolution cross-sectional tissue structures but also vibration parameters, such as the vibration frequency and magnitude of the vocal cord, which provide important information for clinical diagnosis and treatment, as well as in fundamental research of the voice. Office-based OCT is a promising imaging modality to study the larynx.

Paper Details

Date Published: 23 February 2009
PDF: 6 pages
Proc. SPIE 7161, Photonic Therapeutics and Diagnostics V, 716126 (23 February 2009); doi: 10.1117/12.823466
Show Author Affiliations
Lingfeng Yu, Univ. of California, Irvine (United States)
Beckman Laser Institute, Univ. of California, Irvine (United States)
Gangjun Liu, Univ. of California, Irvine (United States)
Beckman Laser Institute, Univ. of California, Irvine (United States)
Marc Rubinstein, Beckman Laser Institute, Univ. of California, Irvine (United States)
UCI Medical Ctr. (United States)
Arya Saidi, Univ. of California, Irvine (United States)
Shuguang Guo, Univ. of California, Irvine (United States)
Beckman Laser Institute, Univ. of California, Irvine (United States)
Brian J. F. Wong, Univ. of California, Irvine (United States)
Beckman Laser Institute, Univ. of California, Irvine (United States)
UCI Medical Ctr. (United States)
Zhongping Chen, Univ. of California, Irvine (United States)
Beckman Laser Institute, Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 7161:
Photonic Therapeutics and Diagnostics V
Henry Hirschberg; Brian Jet-Fei Wong; Kenton W. Gregory; Reza S. Malek; Nikiforos Kollias; Bernard Choi; Guillermo J. Tearney; Justus F. R. Ilgner; Steen J. Madsen; Laura Marcu; Haishan Zeng, Editor(s)

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