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Proceedings Paper

Impact of magnification of imaging system on laser speckle contrast imaging
Author(s): Jianjun Qiu; Hongyan Zhang; Pengcheng Li; Qingming Luo
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Paper Abstract

Laser Speckle Contrast Imaging (LSCI) is becoming a promising optical technique that generates two-dimensional map of blood flow of biological tissues in vivo with high spatiotemporal resolution. Experimental considerations for effective implementation of this technique have been extensively discussed. However, the influence of magnification of imaging system on laser speckle contrast imaging has not been sufficiently studied. In this study, we employ a porcelain plate model experiment to investigate the impact of magnification on statistical characteristic of speckle pattern and on the sensitivity of the measurement. We show that dynamic speckle contrast decreases with increasing magnification while static speckle contrast keeps constant with that. The sensitivity of LSCI has insignificant change throughout the magnifications in our experiments. Our results suggest that dynamic scattering areas with very slow speeds can be discriminated from the static ones, such as discriminating some small vessels from the cortex in cerebral blood flow imaging more efficiently when larger magnification is used.

Paper Details

Date Published: 6 March 2009
PDF: 5 pages
Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 72800Z (6 March 2009); doi: 10.1117/12.823356
Show Author Affiliations
Jianjun Qiu, Huazhong Univ. of Science and Technology (China)
Hongyan Zhang, Huazhong Univ. of Science and Technology (China)
Pengcheng Li, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 7280:
Seventh International Conference on Photonics and Imaging in Biology and Medicine
Qingming Luo; Lihong V. Wang; Valery V. Tuchin, Editor(s)

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