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Proceedings Paper

Photodynamic dosimetry in the treatment of periodontitis
Author(s): Roger C. Andersen; Nicolas G. Loebel; Dane M. Andersen
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Paper Abstract

Photodynamic therapy has been demonstrated to effectively kill human periopathogens in vitro. However, the translation of in vitro work to in vivo clinical efficacy has been difficult due to the number of variables present in any given patient. Parameters such as photosensitizer concentration, duration of light therapy and amount of light delivered to the target tissue all play a role in the dose response of PDT in vivo. In this 121 patient study we kept all parameters the same except for light dose which was delivered at either 150 mW or 220 mW. This clearly demonstrated the clinical benefits of a higher light dose in the treatment of periodontitis.

Paper Details

Date Published: 13 July 2009
PDF: 11 pages
Proc. SPIE 7380, Photodynamic Therapy: Back to the Future, 73803E (13 July 2009); doi: 10.1117/12.822941
Show Author Affiliations
Roger C. Andersen, Ondine Biopharma Corp. (United States)
Nicolas G. Loebel, Ondine Biopharma Corp. (United States)
Dane M. Andersen, Loma Linda Univ. (United States)

Published in SPIE Proceedings Vol. 7380:
Photodynamic Therapy: Back to the Future
David H. Kessel, Editor(s)

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