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Proceedings Paper

The spectrum character of photoreaction of Hypocrellin A and cysteine
Author(s): Jucheng Zhang; Wei Liu; Ying Li; Pei Zhang; Zhongzhou Yi; Yong Min; Zhaolong Huang; Lihua Yao; Haiju Lu
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Paper Abstract

In the current work, Hypocrellin A (HA) is one of the nature photosensitizer was recognized by researchers, and it used as a probe to research the molecular recognition and interaction with protein, the work suggested the HA can as the medicine to treat some disease. This paper study the spectrum character of photoreaction of Hypocrellin A and cysteine in different pH value, the spectrum show an isosbestic point at 495nm, and the absorption peak at 478nm was red-shifted to about 500nm. The result suggested the HA can react with cysteine in this condition, and farther illuminated the cysteine residue may is one of the target of the interaction of HA or HB with protein.

Paper Details

Date Published: 6 March 2009
PDF: 5 pages
Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 72800R (6 March 2009); doi: 10.1117/12.821301
Show Author Affiliations
Jucheng Zhang, Honghe Univ. (China)
Wei Liu, Honghe Univ. (China)
Ying Li, Honghe Univ. (China)
Pei Zhang, Honghe Univ. (China)
Zhongzhou Yi, Honghe Univ. (China)
Yong Min, Honghe Univ. (China)
Zhaolong Huang, Honghe Univ. (China)
Lihua Yao, Honghe Univ. (China)
Haiju Lu, Honghe Univ. (China)


Published in SPIE Proceedings Vol. 7280:
Seventh International Conference on Photonics and Imaging in Biology and Medicine
Qingming Luo; Lihong V. Wang; Valery V. Tuchin, Editor(s)

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