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Proceedings Paper

Optimization of a multi-well array SERS chip
Author(s): J. L. Abell; J. D. Driskell; R. A. Dluhy; R. A. Tripp; Y.-P. Zhao
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Paper Abstract

SERS-active substrates are fabricated by oblique angle deposition and patterned by a polymer-molding technique to provide a uniform array for high throughput biosensing and multiplexing. Using a conventional SERS-active molecule, 1,2-Bis(4-pyridyl)ethylene (BPE), we show that this device provides a uniform Raman signal enhancement from well to well. The patterning technique employed in this study demonstrates a flexibility allowing for patterning control and customization, and performance optimization of the substrate. Avian influenza is analyzed to demonstrate the ability of this multi-well patterned SERS substrate for biosensing.

Paper Details

Date Published: 4 May 2009
PDF: 11 pages
Proc. SPIE 7321, Bio-Inspired/Biomimetic Sensor Technologies and Applications, 732103 (4 May 2009); doi: 10.1117/12.820358
Show Author Affiliations
J. L. Abell, The Univ. of Georgia (United States)
J. D. Driskell, The Univ. of Georgia (United States)
R. A. Dluhy, The Univ. of Georgia (United States)
R. A. Tripp, The Univ. of Georgia (United States)
Y.-P. Zhao, The Univ. of Georgia (United States)

Published in SPIE Proceedings Vol. 7321:
Bio-Inspired/Biomimetic Sensor Technologies and Applications
Nicholas F. Fell Jr.; Venkataraman S. Swaminathan, Editor(s)

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