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Proceedings Paper

Photochemical effects in the lens from near infrared radiation?
Author(s): Per G. Söderberg; Riyadh Al-Saqry; Karl Schulmeister; Konstantin Gallichanin; Martin Kronschläger; Zhaohua Yu
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Paper Abstract

Conclusion: The current data are consistent with a potential photochemical effect of in vivo exposure of the crystalline lens to near infrared radiation since the onset of cataract after in just above threshold dose was at least 18 hrs delayed after the exposure. Materials and methods: The eyes of 6 weeks old Sprague-Dawley rats were exposed unilaterally in vivo to 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. First, four exposure time groups of rats were exposed to increasing exposure times. At 24 hrs after exposure, the difference of light scattering between the lenses from the same animal was measured. Then, based on the first experiment, four post-exposure time groups were exposed unilaterally in vivo to 8 s of 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. After, the intended post-exposure time, the difference of light scattering between the lenses from the same animal was measured. Results: A 3 mm spot of 6.2 W induces light scattering in the lens with exposures of at least 8 s. Further, after 8 s of 6.2 W within a 3 mm spot on the lens surface, the light scattering increase in the lens was delayed at least 18 hrs after the exposure.

Paper Details

Date Published: 23 February 2009
PDF: 5 pages
Proc. SPIE 7163, Ophthalmic Technologies XIX, 716311 (23 February 2009); doi: 10.1117/12.816848
Show Author Affiliations
Per G. Söderberg, Uppsala Univ. (Sweden)
Univ. of Miami (United States)
Riyadh Al-Saqry, Uppsala Univ. (Sweden)
Karl Schulmeister, Austrian Research Ctrs. (Austria)
Konstantin Gallichanin, Uppsala Univ. (Sweden)
Martin Kronschläger, Uppsala Univ. (Sweden)
Zhaohua Yu, Uppsala Univ. (Sweden)


Published in SPIE Proceedings Vol. 7163:
Ophthalmic Technologies XIX
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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